The Mahaney Laboratory in the Department of Neurosurgery at Stanford University School of Medicine studies the intraventricular hemorrhage (IVH)-induced post-hemorrhagic hydrocephalus (PHH) and has demonstrated that elevated levels of hemoglobin and ferritin in the CSF of preterm neonates are associated with development of PHH and severe ventricular enlargement. Our research currently focuses on (1) discovering CSF biomarkers for prediction and early diagnosis of PHH in neonates with IVH and (2) developing novel therapies with our animal hydrocephalus model that is equivalent to the brain maturity of human preterm neonates (i.e., 33 to 36 weeks’ gestation in humans). Our goal is to translate the results from our studies to diagnosis and treatment of children with hemorrhage-induced hydrocephalus.
We are seeking a Life Science Research Professional 1 who has experience in both wet and dry lab research. Successful candidates are expected to perform or assist with stereotactic small animal surgery, medical imaging (e.g., MRI), microscopy (e.g., confocal imaging, SEM of brain tissues), neurobehavioral assays, biochemical experiments, and bioinformatic analysis of transcriptomic and/or proteomic data.
Minimum Requirements:
- Bachelor's degree in Biology, Biochemistry, Neurobiology, Bioengineering, or related scientific field with four years of relevant research experience or Master’s degree in Biology discipline or Bioinformatics with two years of relevant research experience.
- Comprehensive understanding of scientific principles.
- Strong analytical skills.
Desired Qualifications:
- Strong experience in rat/mouse handling.
- Experience in animal surgeries and behavior assays.
- Hands-on experience in biological/biochemical assays (e.g., qPCR, ELISA, WB, FACS, etc).
- Experience in prep of histology samples (brain tissues are preferred).
- Experience in confocal microscopy and electron microscopy (e.g., SEM, TEM).
- Experience in primary cell cultures.
- Experience in single-cell RNA-Seq of tissues (e.g., tissue dissociation, cell sorting, library construction and analysis of sequenced data).
- Strong interpersonal and communication skills.
EDUCATION & EXPERIENCE (REQUIRED):
Bachelor's degree in related scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
- General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
- Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
- Ability to maintain detailed records of experiments and outcomes.
- General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
- Ability to work under deadlines with general guidance.
- Excellent organizational skills and demonstrated ability to accurately complete detailed work.
PHYSICAL REQUIREMENTS*:
- Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous environment.
- Position may require repetitive motion.
*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
WORKING CONDITIONS:
- May require working in close proximity to blood borne pathogens.
- May require work in an environment where animals are used for teaching and research.
- Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
- Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research requirements and business needs.
WORK STANDARDS:
- Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
- Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors bases on training and lessons learned.
- Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University’s Administrative Guide, http://adminguide.stanford.edu.
The expected pay range for this position is $26.44 to $36.54 per hour.
Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs.
At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https:/lcardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford's extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process.
Consistent with its obligations under the law, the University will provide reasonable accommodations to applicants and employees with disabilities. Applicants requiring a reasonable accommodation for any part of the application or hiring process should contact Stanford University Human Resources at
stanfordelr@stanford.edu. For all other inquiries, please submit a contact form.
Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.
