Stanford University is seeking a Life Science Research Professional 3 to perform complex functions and activities involved in defined research projects, and independently conduct a major portion of the research project(s).
About the Department of Pathology:
Comprised of extraordinary faculty and staff, our mission is to improve the ability to diagnose, treat and understand the origin and manifestation of human disease, and to care for those who have or are at risk to develop disease. We accomplish this through our clinical services (in all fields of anatomic and clinical pathology, including molecular and genomic pathology, histocompatibility testing and transfusion medicine) and research (which includes basic, translational and clinical research into the origins and manifestations of disease, including efforts to improve disease prediction and prevention as part of the goal of achieving precision medicine and health), and also by educating future leaders in pathology and related fields. Everything we do is to achieve the goals of providing the highest quality of clinical services to the patients for whom we passionately care for, to advance our ability to understand, diagnose, monitor and ultimately to cure disease or to prevent or delay its occurrence, and to provide outstanding education and career development opportunities to those who share these goals.
For more information about the department visit http://pathology.stanford.edu/
About the Lab:
In the lab of Dr. Long at Stanford (Department of Pathology and ChEM-H) the overarching goal is to understand the molecular pathways of metabolic homeostasis. We use metabolomics and proteomics technologies as discovery tools. We combine these tools with classical biochemical and genetic approaches in cell and animal models. We engage in extensive collaborations with clinicians at Stanford and elsewhere. Our goal is to uncover fundamental signaling pathways that control organismal energy metabolism.
About the Position:
We are seeking a highly talented, driven, and motivated Life Science Research Professional 3 to join the Long Lab as a senior scientist to investigate novel biological mechanisms and potential therapeutic targets to treat metabolic disease. The successful candidate will lead projects that advance our understanding of the biochemical, cellular, and molecular mechanisms of the endocrine system, with a main emphasis on identifying signaling pathways that regulate glucose, lipid, and energy homeostasis.
The candidate will be expected to work independently and collaboratively on pipeline projects and will be responsible for advancing exciting and novel research stage programs, providing both scientific and technical expertise and generating solid proof of concept data. Excellent communication skills will facilitate fruitful and open collaborations with others in the Long lab and also other laboratories at Stanford University. Time and space will be provided to drive both pipeline research and also explore new biologies and pathways for new target discovery. Using state of the art techniques and technologies, the candidate will have the capacity to develop in vitro and in vivo skills to test the involvement of novel pathways and molecules in the pathogenesis of metabolic diseases and to identify the mechanism of action (MOA) of new targets.
Duties Include:
- Design research approaches for a major portion of research project(s), including background research, experimental design and execution, problem-solving, and writing up for publication.
- Develop new protocols; test and evaluate a variety of approaches.
- Perform complex (lab and/or field) experiments, and maintain detailed records of experiments and outcomes; analyze and interpret research data resulting from original procedures and methods.
- Prepare periodic progress reports or written reports on all phases of the research project.
- Contribute substantively to the preparation of papers for publication, especially in the results section. May be a co-author on publications. Present ongoing work and findings to colleagues at academic conferences.
- Perform ongoing literature review to remain current with new procedures and related research; propose new research directions based on new advances discussed in literature.
- Work with health and safety department to ensure lab complies with regulations and all required trainings.
- Formally supervise and train new staff or students as needed, including hiring, performance management, and related duties, in addition to instruction on techniques and consultation on project work.
Desired Qualifications:
- Ph.D. in biochemistry, molecular biology, cell biology or related science field.
- Excellent organizational, communication, and problem solving skills
- Demonstrated success through first author publications or other quantifiable achievements
- Demonstrated ability to complete detailed work accurately
- Independently designing, executing and interpreting experiments
- Extensive hands-on experience in cellular and molecular biochemical techniques including primary cell isolation from tissues, ELISAs, flow cytometry and in vivo animal models
- Can present research at intra- and inter-lab meetings
Education & Experience (Required):
- Bachelor's degree in related scientific field and four years of relevant work experience; or Master’s degree in a related scientific field and two years relevant experience; or PhD in related science field.
Knowledge, Skills, and Abilities (Required):
- Comprehensive understanding of scientific principles.
- Expert level knowledge and skills in field of science related to research project.
- General computer skills, experience with databases and scientific applications, and ability to quickly learn and master computer programs.
- Strong analytical skills and excellent judgment.
- Ability to work under deadlines with general guidance is essential.
- Excellent organizational skills and demonstrated ability to complete detailed work accurately.
- Developing project management skills.
Physical Requirements:
- Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 50 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous environment.
- Position may require repetitive motion.
Working Conditions:
- May require working in close proximity to blood borne pathogens.
- May require work in an environment where animals are used for teaching and research.
- Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
- Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research requirements and business needs.
- Due to the nature of the work, this position will work fully on-site.
Why Stanford is for You:
- Freedom to grow. We offer career development programs, tuition reimbursement, or course auditing. Join a TedTalk, film screening, or listen to a renowned author or global leader speak.
- A caring culture. We provide superb retirement plans, generous time-off, and family care resources.
- A healthier you. Climb our rock wall or choose from hundreds of health or fitness classes at our world-class exercise facilities. We also provide excellent health care benefits.
- Discovery and fun. Stroll through historic sculptures, trails, and museums.
- Enviable resources. Enjoy free commuter programs, ride-sharing incentives, discounts and more.